Some actors, like Chris Evans and Gemma Chan, have played two characters in the MCU. However, thanks to his appearance in Deadpool & Wolverine, MCU veteran Nathan Fillion holds the record for the most Marvel roles. The actor (a frequent collaborator with James Gunn) was previously tied for the record with Patton Oswalt, who played separate characters in Blade: Trinity, Agents of Shield, and MODOK. However, Fillion’s newest cameo has earned him the top spot.

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